The Skeptics' Guide to EM

SEPTEMBER 21, 2024

Date: September 18, 2024 Reference: Dillon et al. Naloxone is a well-established medication used primarily for reversing opioid overdoses. Traditionally, naloxone has been used in cases of suspected opioid overdose where patients exhibit signs of severe respiratory depression or loss of consciousness (LOC). JAMA Network Open.

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Naloxone NARCAN Overdose CPR 262

Dr. Smith's ECG Blog

MAY 5, 2023

Narcan was not given at the scene. Numerous needles from self-injection of opioids were found in the car. There was no indication of hyperkalemia.

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E-9-1-1 NARCAN Naloxone Overdose 52

ALiEM

JANUARY 6, 2025

Necrotizing fasciitis Case Question: Will naloxone reverse a xylazine overdose? No, xylazine is a non-narcotic drug and is not an opioid, thus, Narcan will not specifically reverse acute xylazine intoxication. References Papudesi, Bhavani Nagendra, et al. However, fentanyl is the most common drug combined with xylazine.

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ACEP Now

FEBRUARY 11, 2025

He was admitted for a suspected kratom overdose and acute kratom withdrawal. 7 Most of the difficulty in identifying patients who have overdosed or are in acute withdrawal from kratom comes from the inability to test for it in commercial assays of blood or urine. Gummin DD, Mowry JB, Beuhler MC, et al. Clin Toxicol (Phila).

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NARCAN Naloxone Overdose Mental Health Services 89

EMDocs

JANUARY 22, 2025

Background: Fentanyl has contributed to a significant increase in drug overdose deaths in recent years. A prospective study of 453 patients who were admitted after receiving naloxone reported life-threatening complications in over 1% of heroin-overdosed patients. Clinical Pearls: Naloxone is lifesaving in opioid overdoses.

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Naloxone E-9-1-1 Overdose NARCAN 97