article thumbnail

ToxCard: Second Generation Antipsychotic Overdose

EMDocs

Questions: What are the symptoms of second-generation antipsychotic overdose? How is second-generation antipsychotic overdose diagnosed? What is the treatment for patients who have overdosed on second-generation antipsychotics? 4 The specific incidence of second-generation antipsychotic drug overdose is unknown, however, 4.7%

Overdose 111
article thumbnail

Updates in High dose Insulin and Euglycemia Therapy (HIET) for the treatment of Beta-adrenergic Receptor and Calcium Channel Antagonists Overdose

Core EM

Background: An update to our 2015 post on HIET for beta-adrenergic receptor and calcium channel antagonists overdose. Beta-adrenergic receptor antagonists (Beta blockers, BB) and calcium channel antagonists (calcium channel blockers) are common drugs that can produce profound cardiac depression and shock when taken in overdose.

Overdose 246
professionals

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

SGEM#453: I Can’t Go For That – No, No Narcan for Out-of-Hospital Cardiac Arrests

The Skeptics' Guide to EM

Date: September 18, 2024 Reference: Dillon et al. Naloxone is a well-established medication used primarily for reversing opioid overdoses. Traditionally, naloxone has been used in cases of suspected opioid overdose where patients exhibit signs of severe respiratory depression or loss of consciousness (LOC). JAMA Network Open.

Naloxone 260
article thumbnail

SGEM#407: Here We Go Test Strips for Fentanyl

The Skeptics' Guide to EM

Date: June 16, 2023 Reference: Reed et al. Date: June 16, 2023 Reference: Reed et al. EDs are an important touch point for individuals with opioid use disorder (OUD), given the number of encounters for overdose and complications associated with drug use. Reference: Reed et al. AEM June 2023 Guest Skeptic: Dr. .

Overdose 195
article thumbnail

ACMT Toxicology Visual Pearl: Needle to Necrosis

ALiEM

Recently, xylazine has gained attention in the media with increasing reports of xylazine-related overdose deaths in patients. When combined with illicit opioids such as heroin and fentanyl, xylazine may increase the risk of fatal overdose given the augmented sedation and respiratory depression effects [2]. MMWR Morb Mortal Wkly Rep.

Naloxone 169
article thumbnail

SGEM#241: Wake Me Up Before You Go, Go – Using the HOUR Rule

The Skeptics' Guide to EM

Date: January 17th , 2019 Reference: Clemency et al. Date: January 17th , 2019 Reference: Clemency et al. The EMS crew observes drug paraphernalia and suspect an intravenous (IV) opioid overdose. 1] Two-thirds of the all the drug overdoses in the US in 2016 (63,632) involved an opioid (42,249). [2]

Naloxone 130
article thumbnail

20-something with huge verapamil overdose and cardiogenic shock

Dr. Smith's ECG Blog

A 20-something presented after a huge verapamil overdose in cardiogenic shock. And she does not know that this is an overdose; she thinks it is a patient with chest pain!! Comment on High Dose Insulin and Calcium Channel Blocker Overdose I do not have any explanation for the ST-T abnormalities here. The initial K was 3.0