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2023 AHA Update on Management Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning

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Opioid overdose remains the leading cause of cardiac arrest due to poisoning in North America. Lay and trained responders should not delay acti- vating emergency response systems while await- ing the patient’s response to naloxone or other interventions. No NAC or ascorbic acid. COR 1, LOE C-EO. COR 2a, LOE B-NR.

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