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Opioid overdose remains the leading cause of cardiac arrest due to poisoning in North America. Naloxone administration may reverse respiratory arrest, preventing progression to cardiac arrest. Editorial Comment: Naloxone first, flumazenil only for pure benzo’s (e.g., COR No Benefit, LOE C-EO. COR Harm, LOE B-R.
The 50-something patient with history of coronary stenting and slightly reduced LV ejection fraction. He awoke with naloxone. which would suggest reduced rates of major adverse cardiac events with coronary artery bypass grafting." He had been smoking an opiate and suddenly collapsed. He was ventilated with BVM on arrival.
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