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Podcast 185.0: Anticoagulation Reversal

Core EM

Hosts: Joe Offenbacher, MD Audrey Bree Tse, MD [link] Download Leave a Comment Tags: Anticoagulation , Critical Care , Resuscitation Show Notes Coagulation Cascade: Algorithm for Anticoagulated Bleeding Patient in the ED: Indications for Anticoagulation Reversal: References: Baugh CW, Levine M, Cornutt D, et al. Iran J Pharm Res.

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Episode 21: Trauma resuscitation with Scott Weingart

Critical Care Scenarios

Continue to use a balanced ratio unless you can use TEG to guide FFP and platelets.* FFP is delayed or unavailable; 2. Our 1st anniversary episode! Takeaway lessons * In an ideal world, penetrating abdominal trauma in an unstable patient would proceed directly to the OR with no delay by the ED. Empiric cryo not a bad idea early.

FFP 100
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Thrombotic Thrombocytopenic Purpura (TTP)

Core EM

Joly, 2017; Sawler, 2020) Fresh frozen plasma (FFP) (contains ADMTS-13) may be used to supplement ADAMTS-13 if there is a delay in initiating TPE in the emergency department (i.e. The first TPE session should be completed prior to administration of any biologic therapies. Initiation and dosing should be discussed with hematology.

Plasma 246
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Episode 68: Liver transplant with Meera Gupta

Critical Care Scenarios

FFP is usually not given prophylactically. . * Chronic thrombocytopenia is common and is monitored to determine when DVT prophylaxis can be started. Platelets >20k are targeted. * If INR >2, vitamin K is given empirically. Bleeding is usually considered a little preferable to clotting, in terms of ease of treatment. *

FFP 130
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Tasty Morsels of Critical Care 001 | Thrombotic Thrombocytopaenic Purpura

Emergency Medicine Ireland

Welcome back to the tasty morsels of critical care podcast. Read More » Welcome back to the tasty morsels of critical care podcast. Theoretically giving them FFP while waiting on PLEX seems like it might be sensible but in reality probably does nothing when the autoantibodies are still around.

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EM@3AM: Amniotic Fluid Embolism

EMDocs

Treatment is supportive with respiratory therapy, critical care, inotropic therapy, and cardiac life support. If AFE occurs during labor, immediate delivery is recommended.

EMS 111
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Best Practices for Upper Gastrointestinal Hemorrhage

ACEP Now

Fresh frozen plasma, or FFP, should only be given to cirrhotic patients as part of the massive transfusion protocol in cases of profound hypotension, as “patients with cirrhosis rarely have true enzymatic hypocoagulability, and FFP may worsen bleeding due to over-resuscitation and dilution of coagulation factors.”