E-9-1-1 Overdose Plasma 
EMDocs
APRIL 10, 2024
1-5] Since then, many more medications have been developed and deployed. Metabolism of ester anesthetics is by plasma cholinesterase, whereas amides are metabolized by the cytochrome P450 system in the liver. [6] 6] Action of local anesthetics is dependent upon the molecule crossing the plasma membrane in a unionized form. [2]
EMDocs
SEPTEMBER 7, 2023
1 Clinical Questions: When should a clinician suspect diethylene glycol (DEG) toxicity? DEG is rapidly absorbed when ingested and can reach peak plasma and brain tissue concentrations within four hours of ingestion. Elimination half-life data is not well established but increases in larger overdoses and as renal injury begins to occur.
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