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In: UptoDate, Feldweg AM (ed.) Angioedema in the Emergency Department: An Evidence Based Review. Emergency Medicine Practice. EBMedicine.net. 2012; 14(11). Zuraw et al. An overview of angioedema: Clinical features, diagnosis, and management. UpToDate, Waltham, MA. Clinical practice. Hereditary angioedema. N Engl J Med. 2008;359(10):1027-1036.
Most major hemorrhage protocols give a balanced transfusion of PRBCs, FFP, and platelets in ratios approaching concentrations found in whole blood. Fibrinogen and fibrin are often depleted during major trauma as a result of consumption, breakdown, and dilution. Fibrinogen products may also be needed to stabilize clots and stem bleeding.
A 37-year-old G5P4 at 33 weeks presents to the ED after being brought in by ambulance. The absence of preeclampsia symptoms prior to the acute event makes eclampsia less likely. We’ll keep it short, while you keep that EM brain sharp. She had a precipitous delivery while the ambulance was pulling in.
Fresh frozen plasma, or FFP, should only be given to cirrhotic patients as part of the massive transfusion protocol in cases of profound hypotension, as “patients with cirrhosis rarely have true enzymatic hypocoagulability, and FFP may worsen bleeding due to over-resuscitation and dilution of coagulation factors.” Am J Emerg Med.
Not so much for the patient but it’s one of those ones that is niche enough to not have been picked up via the usual filters of ED, medical team to the ward. Theoretically giving them FFP while waiting on PLEX seems like it might be sensible but in reality probably does nothing when the autoantibodies are still around.
Studies from the 1980s and 1990s found 5-14% of patients with hemoptysis had a life-threatening event (7,8). Airway: Key decision: base decision for intubation on clinical course, efficacy of airway clearance (coughing, mental status), ED/institutional resources, respiratory status (respiratory failure). Wide range in numbers for MH.
Ali, a 12-year-old male, is pre-alerted by ambulance to ED. How would you prepare for the patient’s arrival to ED? Do I have emergency blood available in the ED? Lee, a 14-year-old male, is brought into the ED by his friends, stating he has been in a fight. Which investigations would you consider?
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