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Questions: What are the symptoms of second-generation antipsychotic overdose? How is second-generation antipsychotic overdose diagnosed? What is the treatment for patients who have overdosed on second-generation antipsychotics? 4 The specific incidence of second-generation antipsychotic drug overdose is unknown, however, 4.7%
Aaron Orkin discuss the latest in naloxone in opioid overdose cardiac arrest and altered LOA, a 5-step approach to ED opioid withdrawal management and how we can improve mortality and morbidity in patients with opioid use disorder in the era of the opioid epidemic.
He currently practices emergency medicine in New Mexico in the ED, in the field with EMS and with the UNM Lifeguard Air Emergency Services. Naloxone is a well-established medication used primarily for reversing opioid overdoses. Before attending medical school, he was a New York City Paramedic.
Case: A 27-year-old right hand dominant patient presents to the emergency department (ED) with a 2.5 EDs are an important touch point for individuals with opioid use disorder (OUD), given the number of encounters for overdose and complications associated with drug use. cm left forearm abscess. Reference: Reed et al.
A 20-something presented after a huge verapamil overdose in cardiogenic shock. mg/dL (sorry, Europeans, for the weird units) Here was the initial ED ECG: There is a junctional rhythm with retrograde P-waves (see the dip in the T-wave in lead II across the bottom; you can follow that up to all the other leads and see the retrograde P wave).
Background Information: Opioid overdose deaths have been increasing in the past twenty years. The national number of overdose deaths from any opioid has increased 62.5% In addition, buprenorphine has a lower risk of death from overdose when compared to methadone (2). PMID 33392580.
Recently, xylazine has gained attention in the media with increasing reports of xylazine-related overdose deaths in patients. When combined with illicit opioids such as heroin and fentanyl, xylazine may increase the risk of fatal overdose given the augmented sedation and respiratory depression effects [2]. Published May 2023.
The EMS crew observes drug paraphernalia and suspect an intravenous (IV) opioid overdose. Background: There have been close to 400,000 deaths from an overdose involving any opioid (prescription and illicit opioids) between 1999 and 2017. [1] Wave 2: Rapid increase in overdose deaths involving heroin starting in 2010.
Case: You are doing great things and helping many patients during your shift in the emergency department (ED) when you hear a trauma alert being called overheard. She is an Assistant Professor and Director of Research in the Department of Emergency Medicine at the NYU Grossman Long Island Hospital Campus.
In 2023, EMS clinicians responded to 236,000 calls for suspected opioid overdoses, representing nearly 2% of all EMS calls nationwide. The 2024 ESO EMS Index reveals that 82% of patients with suspected opioid overdoses received naloxone, a medication that can reverse opioid effects.
In anticipation of EM Cases Episode 116 on Opioid Misuse, Overdose and Withdrawal, Dr. Michelle Klaiman, Addictions and Emergency Medicine specialist, tells her Best Case Ever exemplifying how we can positively impact the lives of ED patients for years to come - even when they present with simple, run-of-the-mill diagnoses - by thinking outside the (..)
One of the things we need to think about whenever we see a patient who’s going low and slow with hypotension and bradycardia is an overdose. And inevitably we’re gonna be faced with both intentional and unintentional overdoses from these drugs in the ED.
REBEL Cast Ep120: Etomidate vs Ketamine for RSI in the ED? PMID: Clinical Question: Does a single dose of ketamine or etomidate used for rapid sequence intubation (RSI) of critically adults in the ED impact the SOFA score within 3 days of hospitalization? Click here for Direct Download of the Podcast Paper: Knack SKS et al.
A 27 year old man is brought to your ED by ambulance after taking an overdose of a commonly used medication. He is tachypnoeic with a normal mental state and blood pressure. His ABG (RA) shows:
Just give them a choice”: Patients’ perspectives regarding starting medications for opioid use disorder in the ED. Just give them a choice”: Patients’ perspectives regarding starting medications for opioid use disorder in the ED. Case: A 24-year-old male presents to the emergency department (ED) after a fentanyl overdose.
18 year old man was brought to ED with an overdose of unknown medication. He was intoxicated and very agitated. He needed 4 security guards to restrain him so a medical officer can put a cannula an…
A 65 year old female is brought to ED via ambulance on a priority 1. According to the paramedics the patient has taken an overdose of benzodiazepines and alcohol. Her GCS is 3 and the team is prepa…
A 65 year old female is brought to ED via ambulance on a priority 1. According to the paramedics the patient has taken an overdose of benzodiazepines and alcohol. Her GCS is 3 and the team is prepa…
A 65 year old female is brought to ED via ambulance on a priority 1. According to the paramedics the patient has taken an overdose of benzodiazepines and alcohol. Her GCS is 3 and the team is prepa…
A 65 year old female is brought to ED via ambulance on a priority 1. According to the paramedics the patient has taken an overdose of benzodiazepines and alcohol. Her GCS is 3 and the team is prepa…
Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy. Successful treatment of flecainide-induced cardiac arrest with extracorporeal membrane oxygenation in the ED. Am J Emerg Med. 2022 Jun;56:394.e1-394.e4. doi: 10.1016/j.ajem.2022.03.006. 2022.03.006. Epub 2022 Mar 9. J Med Toxicol.
Case: A 54-year-old female presents to the emergency department (ED) with abdominal pain and profuse non-bloody diarrhea for the past 24 hours. Background: Preventable adverse drug events (ADEs) are a common cause of ED visits, hospitalizations and death (Ref 1,2). Reference: Hohl C et al. AEM Aug 2018.
Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics. A multicenter comparison of the safety of oral versus intravenous acetylcysteine for treatment of acetaminophen overdose [published correction appears in Clin Toxicol (Phila). Adverse reactions to acetylcysteine and effects of overdose.
She had return of spontaneous resuscitation (ROSC) and was subsequently intubated and transported to the emergency department (ED). Upon ED arrival, she had a heart rate (HR) of 160 and blood pressure (BP) of 80s/40s. What are the treatment options for a benzonatate overdose? Questions: What is benzonatate’s mechanism of action?
Questions: What are the clinical manifestations of bupropion overdose? How is bupropion overdose treated? How long should a patient be observed after a bupropion overdose? 1 In addition to intentional overdoses, there are multiple case studies of abuse (ingestion, insufflation, injection). hours, SR 3 hours, XL 5 hours.
Broselow-Luten System: Supportive Data Physician estimates of weight can underdose children by 49% or overdose by up to 116%. Sinha 2012] It is useful in the prehospital setting , correlating well with actual weight and ED Broselow weight. Reduces dosing errors during resus, up to 33.88%. Recommended by ATLS and PALS.
This post will focus on the key parts of the guideline that affect ED evaluation and management. Opioid overdose remains the leading cause of cardiac arrest due to poisoning in North America. Give naloxone for suspected opioid overdose and respiratory compromise/arrest. Top 10 Take Home Pearls 1. COR No Benefit, LOE C-LD.
14-year-old Katy presents to the paediatric Emergency Department (ED), alone, complaining of suicidal ideation. Mental health-related ED visits for children and young people are common and have been on the rise during the last decade. What is the problem? It can be difficult to diagnose and may require detailed investigation.
7,10 Contraindications include asthma, chronic obstructive pulmonary disease (COPD), genitourinary or gastrointestinal obstruction, or if there is suspected or confirmed tricyclic antidepressant (TCA) overdose. His vitals also improve, and he is subsequently discharged from the ED. 9 Physostigmine dosing: 0.5-2 McGraw Hill; 2019.
The patient was brought to the ED and had this ECG recorded: What do you think? After 1 mg of epinephrine they achieved ROSC. Total prehospital meds were epinephrine 1 mg x 3, amiodarone 300 mg and 100 mL of 8.4% sodium bicarbonate. And what do you want to do? The ECG shows severe ischemia, possibly posterior OMI.
The opioid epidemic is not new to ED providers across the country, but the true extent of harm is quite shocking. The North American opioid crisis is rapidly expanding, resulting in unprecedented levels of harm and strain on the healthcare system.
The patient was restless, agitated, and nonverbal on arrival to ED, with elevated HR at 150. Here is the first ED ECG: What is the likely diagnosis? These findings are nearly pathognomonic of, or at least highly suspicious for, tricyclic antidepressant (TCA) overdose. More still on TCA overdose, from lifeinthefastlane.
These medications are a vital tool in the care of ED patients, from simple local analgesia for a laceration repair to regional analgesia for painful procedures. doi:10.1007/BF03161199 Olson K, Smollin C, eds. Poisoning & Drug Overdose. 1-5] Since then, many more medications have been developed and deployed. 2022;59:42-48.
1,2 With such enormous popularity it is no surprise that each year there are 56,000 emergency department (ED) visits, 2,600 hospitalizations, and 500 deaths in the U.S. 1,2 With such enormous popularity it is no surprise that each year there are 56,000 emergency department (ED) visits, 2,600 hospitalizations, and 500 deaths in the U.S.
The fourth episode in this series will shift gears and talk about safely transporting children to the ED via prehospital services. Haloperidol (Haldol) – 0.5-5 5 mg PO; 0.05-0.15 mg/kg IM (up to 5 mg/dose) Chlorpromazine (Thorazine) – 0.55 mg/kg/dose (PO/IM) Droperidol – 0.03-0.07 mg/kg/dose (PO/IM/IV) Midazolam – 0.25-0.5
The PREOXI trial compared oxygen mask pre-oxygenation versus noninvasive positive-pressure ventilation (NIPPV) in patients requiring intubation in emergency departments (EDs) and intensive care units. 2 This was not an ED trial but was performed in stable patients on the inpatient wards. The obvious winner was NIPPV, whose 9.1
After discussing all of the above with ED staff, we have made a decision to get stat echocardiogram and assess overall LV function and wall motion abnormalities and defer cath lab activation at the time." On the other hand, stable EKG over an hour in the setting of ongoing acute coronary syndrome is again unusual.
mL/kg/hr for 2 consecutive hours OR Decrease in serum lactate by more than 10% from initial level Primary outcome – Early norepinephrine group vs. the control group demonstrated higher rates of shock control at 6 hours: 76.1% vs 48.4% (OR 3.4, vs 48.4% (OR 3.4,
56 year old male presents to ED after taking an unknown quantity of perindapril/indapamide combination 6 hours previously. He also … Continue reading →
Louis) // Reviewed by: Alex Koyfman, MD (@EMHighAK); Brit Long, MD (@long_brit) Case You are working in the trauma/critical care pod of your emergency department (ED). His blood sugar was normal en route to the ED, and his initial rhythm on the cardiac monitor was asystole. It is unclear how long he was down.
Today’s episode of the podcast is a myth busting on all the media reports about first responders overdosing by being exposed to fentanyl in the field by incidental contact. 100 micrograms is not enough to cause an overdose in an adult. Even if you were to try to overdose on fentanyl patches this is next to impossible.
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