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Tranq dope (fentanyl-xylazine combination): A new horizon in opioid withdrawal treatment

ALiEM

Bupe Allergy Buprenorphine induction has been the mainstay of emergency department treatment of opioid use disorder for more than a decade [11, 12]. Treating patients with SUD can be incredibly challenging, especially without a foundation in trauma-informed care principles [20]. Or one can start methadone induction.

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ACMT Toxicology Visual Pearl: Needle to Necrosis

ALiEM

Naloxone will not reverse the effects of xylazine; however, it is routinely given in unresponsive or obtunded patients presenting with an opioid toxidrome. In patients with minimal response to naloxone, xylazine toxicity may be suspected [10]. Opioid overdoses involving xylazine in emergency department patients: a multicenter study.

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REBEL Cast Ep117: Low Dose vs Standard Dose Take-Home Buprenorphine From the ED

REBEL EM

Background Information: Opioid overdose deaths have been increasing in the past twenty years. Microdosing and standard‐dosing take‐home buprenorphine from the Emergency Department: A feasibility study. Journal of the American College of Emergency Physicians Open , 1 (6), 1712–1722. PMID 33392580.

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Are Opiates Futile in Low Back Pain?

ACEP Now

1 The emergency department remains an important frontier for work in judicious prescribing, but opiate analgesia remains a valuable tool for the initial treatment of a variety of presentations. The addition of naloxone to the tablets may also provide a confounder in terms of the analgesia provided.

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September 2023 News from the College

ACEP Now

Understanding how and why our biases work is an important first step in improving our decision-making, determining information we’re willing to trust, and building relationships. Did you know our brains are wired to take short cuts that sometimes lead to cognitive distortions?

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ToxCard: Naloxone – Pearls and Pitfalls

EMDocs

In the field, he was given 4 mg intranasal (IN) naloxone and rescue breaths via bag valve mask. He is administered 2mg intravenous (IV) naloxone and shortly after develops precipitated withdrawal with altered mental status, diaphoresis, vomiting, and diarrhea. When should a naloxone infusion be considered?

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SAEM Clinical Images Series: Xylazine Wounds

ALiEM

The pain worsened today, prompting him to come to the emergency department for evaluation. Necrotizing fasciitis Case Question: Will naloxone reverse a xylazine overdose? The patient reported a wound to his left leg that had become larger over the past 5 months. BMP : Na 126; K+ 5.9; up from 0.69) ESR : >100 CRP : 15.94

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