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REBEL Cast Ep 118: The PROCOAG Trial – 4F-PCC for Trauma Patients?

REBEL EM

Reversal of Trauma-Induced Coagulopathy Using First-Line Coagulation Factor Concentrates or Fresh Frozen Plasma (RETIC): A Single-Centre Parallel-Group, Open-Label Randomised Trial. Severe acute traumatic coagulopathy = PT >1.5 to 3.33; P = 0.72 to 2.10; P = 0.03 Severe acute traumatic coagulopathy = PT >1.5 to 3.33; P = 0.72

FFP 139
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Penetrating chest trauma

Don't Forget the Bubbles

They found NO difference in drain failure rates ( 11% pigtail vs 13% chest tube P=0.74), total daily volume drained or length of ICU stay between groups. a) A balanced ratio of 1:1:1 (platelets: FFP: packed red cells) The PROPPR trial showed us that balanced ratios are important. in 1:1:2 group; difference, −5.4% [95% CI, −10.4%

E-9-1-1 139
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Tasty Morsels of Critical Care 001 | Thrombotic Thrombocytopaenic Purpura

Emergency Medicine Ireland

TTP is a lovely ICU diagnosis. TTP is a lovely ICU diagnosis. Treatment consists of: * PLEX – actual proper PLEX with plasma replacement as opposed to just washing out all the good stuff and giving albumin as replacement. Welcome back to the tasty morsels of critical care podcast.

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ToxCard: Iron

EMDocs

Antidote : Deferoxamine is a chelating agent derived from Streptomyces pilosus ; binds free iron from plasma and iron inside of cells. Coagulopathy: Parenteral vitamin K and/or fresh frozen plasma (FFP) as clinically indicated. She was initiated on deferoxamine and admitted to the ICU. 2 L/hr in adults.

E-9-1-1 96
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ED care of refugee populations from sub-Saharan Africa

EMDocs

84 All patients with severe malaria need inpatient admission, ideally to the intensive care unit (ICU). 66 ^^ = a form of polio that arises from the oral polio vaccine (OPV) in regions where there is system lack of vaccination or undervaccination. Severe malaria is typically caused by P. Severe malaria management. WHO Guidelines for Malaria.;

ED 73