ToxCard: Local Anesthetic Systemic Toxicity
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APRIL 10, 2024
Metabolism of ester anesthetics is by plasma cholinesterase, whereas amides are metabolized by the cytochrome P450 system in the liver. [6] 6] Action of local anesthetics is dependent upon the molecule crossing the plasma membrane in a unionized form. [2] Poisoning & Drug Overdose. lidocaine) or an ester (e.g.,
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