The Skeptics' Guide to EM

SEPTEMBER 21, 2024

Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in California. Your partner asks if you want to administer naloxone as well. Today’s study looks at the role of naloxone in OHCA. Naloxone is a well-established medication used primarily for reversing opioid overdoses. JAMA Network Open.

Naloxone 260

Naloxone NARCAN Overdose CPR 260

Peter Canning

JANUARY 27, 2024

The FDA this week approved extending the expiration date of all future manufactured Narcan (the 4mg Nasal spray) from 3 years to 4 years. In the case of naloxone, unlike say milk, the product doesn’t spoil and it retains its potency for many years. Yes, naloxone works for years after its expiration date.

NARCAN 59

NARCAN Naloxone Overdose OR 59

Peter Canning

DECEMBER 6, 2023

I take the naloxone out of my med kit, draw up a small amount in a syringe and slowly push it through the IV. Rest, you overdosed. We had to give you naloxone. We had to give you naloxone. We had to give him some narcan.” “He He overdosed?” We gave him a little naloxone and he came around.

Naloxone 52

Naloxone Overdose NARCAN 52

Dr. Smith's ECG Blog

MAY 5, 2023

Narcan was not given at the scene. The "good" news — Treatment with naloxone will probably resolve the bradycardia. Numerous needles from self-injection of opioids were found in the car. There was no indication of hyperkalemia. Figure-4: Review of the 2 long lead rhythm strips from today's case.

E-9-1-1 52

E-9-1-1 NARCAN Naloxone Overdose 52

EM Basic

MARCH 13, 2019

Today’s episode of the podcast is a myth busting on all the media reports about first responders overdosing by being exposed to fentanyl in the field by incidental contact. 100 micrograms is not enough to cause an overdose in an adult. Even if you were to try to overdose on fentanyl patches this is next to impossible.

Naloxone 52

Naloxone Overdose First Responder NARCAN 52

JEMS

APRIL 8, 2025

The animal tranquilizers xylazine and medetomidine are in approximately one-third of the illegal opioids available in the U.S.

Naloxone 52

Naloxone Overdose NARCAN 52

ALiEM

JANUARY 6, 2025

Necrotizing fasciitis Case Question: Will naloxone reverse a xylazine overdose? No, xylazine is a non-narcotic drug and is not an opioid, thus, Narcan will not specifically reverse acute xylazine intoxication. However, fentanyl is the most common drug combined with xylazine.

NARCAN 141

NARCAN Overdose Naloxone Emergency Department 141