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In the field, he was given 4 mg intranasal (IN) naloxone and rescue breaths via bag valve mask. He is administered 2mg intravenous (IV) naloxone and shortly after develops precipitated withdrawal with altered mental status, diaphoresis, vomiting, and diarrhea. When should a naloxone infusion be considered?
A 33-year-old male with a history of drug use presented to the emergency department (ED) for extreme agitation after receiving two doses of 2 mg naloxone by EMS for respiratory depression. He was admitted for a suspected kratom overdose and acute kratom withdrawal. A dexmedetomidine (Precedex) 400 mcg in 0.9 2022;23(1):4-9. J Med Chem.
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